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Article

The impact of the receptor of hyaluronan-mediated motility (RHAMM) on human urothelial transitional cell cancer of the bladder.

PloS one - 1 Jan 2013

Niedworok Christian, Kretschmer Inga, Röck Katharina, Vom Dorp Frank, Szarvas Tibor, Heß Jochen, Freudenberger Till, Melchior-Becker Ariane, Rübben Herbert, Fischer Jens W

Abstract excerpt

UNLABELLED: Hyaluronan (HA) is a carbohydrate of the extracellular matrix with tumor promoting effects in a variety of cancers. The present study addressed the role of HA matrix for progression and prognosis of human bladder cancer by studying the expression and function of HA-related genes. METHODS: Tissue samples of 120 patients with different stages of transitional cell bladder cancer, who underwent surgical...

Topics

Aged
Aged, 80 and over
Animals
Apoptosis
Carcinoma, Transitional Cell
Disease Models, Animal
Disease Progression
Extracellular Matrix Proteins
Female
Gene Knockdown Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heterografts

Humans

Hyaluronan Receptors

Hyaluronic Acid

Immunohistochemistry

Immunophenotyping

Male

Mice

Source

Open in PubMed Open full text

Identifiers

PMID: 24069434
DOI: 10.1371/journal.pone.0075681
PMCID: PMC3775893

Genes

HAS1
HAS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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The impact of the receptor of hyaluronan-mediated motility (RHAMM) on human urothelial transitional cell cancer of the bladder.PMID 24069434Read ↗

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