Article
The impact of the receptor of hyaluronan-mediated motility (RHAMM) on human urothelial transitional cell cancer of the bladder.
PloS one - 1 Jan 2013
Niedworok Christian, Kretschmer Inga, Röck Katharina, Vom Dorp Frank, Szarvas Tibor, Heß Jochen, Freudenberger Till, Melchior-Becker Ariane, Rübben Herbert, Fischer Jens W
Abstract excerpt
UNLABELLED: Hyaluronan (HA) is a carbohydrate of the extracellular matrix with tumor promoting effects in a variety of cancers. The present study addressed the role of HA matrix for progression and prognosis of human bladder cancer by studying the expression and function of HA-related genes. METHODS: Tissue samples of 120 patients with different stages of transitional cell bladder cancer, who underwent surgical...
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