Article

Integral-Omics: serial extraction and profiling of metabolome, lipidome, genome, transcriptome, whole proteome and phosphoproteome using biopsy tissue

2024-09-28

Abstract excerpt

The integrative multi-omics characterization of minute amount of clinical tissue specimens has become increasingly important. Here, we present an approach called Integral-Omics, which enables sequential extraction of metabolites, lipids, genomic DNA, total RNA, proteins, and phosphopeptides from a single biopsy-level tissue specimen. We benchmarked this method with various samples and applied the workflow to perfo...

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Literature Corpus work: a0547d4c-62b9-509c-b971-1724d3e18094
DOI: 10.1101/2024.09.27.614689

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