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Article

A Human-in-the-Loop Large Language Model System Based on the Model Context Protocol for Differential Diagnosis from Electronic Medical Records and Literature

2026-08-21

Abstract excerpt

Diagnostic errors, including misdiagnoses and delayed clinical diagnoses, could affect outcomes of a significant patient population, particularly individuals presenting with rare diseases or non-specific symptoms. From rule-based diagnostic decision supporting systems (DDSS) to large language model (LLM) based tools for clinical reasoning have been developed to address these limitations. However, existing DDSS are...

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Literature Corpus work
a0127320-3c85-5fed-b715-5fcd03bb42a2
DOI
10.64898/2026.08.18.26359085
Open publication

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A Human-in-the-Loop Large Language Model System Based on the Model Context Protocol for Differential Diagnosis from Electronic Medical Records and LiteratureDOI 10.64898/2026.08.18.26359085
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