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Canary in the cardiac-valve coal mine. Flow velocity and inferred shear during prosthetic valve closure –predictors of blood damage and clotting

2022-06-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> To demonstrate a clear link between predicted blood shear forces during valve closure and thrombogenicity that explains the thrombogenic difference between tissue and mechanical valves and provides a practical metric to develop and refine prosthetic valve designs for reduced thrombogenicity. <h4>Methods</h4> Pulsatile and quasi-steady flow systems were used for testing. The...

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Literature Corpus work
a0011947-87d9-5a9e-a1a8-7fc77ed3c093
DOI
10.1101/2022.06.23.497372
Open publication

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Canary in the cardiac-valve coal mine. Flow velocity and inferred shear during prosthetic valve closure –predictors of blood damage and clottingDOI 10.1101/2022.06.23.497372
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