COX-2 Expression Correlation with Tumor-Associated Macrophages Infiltration and Prognosis in Gastric Cancer

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor microenvironment (TME); M1 TAMs have anti-tumor effects, M2 pro-tumor effects. Cyclooxygenase-2 (COX-2) relates to tumor occurrence, development, prognosis and immune infiltration. This study explored COX-2 expression in gastric cancer, its correlation with TAMs and prognostic...

Topics

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• Immunoenzyme Techniques
• Interleukin-10
• Interleukin-12 Subunit p40
• Neoplasm Invasiveness
• Peritoneal Neoplasms
• Vascular Endothelial Growth Factor A
• Vascular Endothelial Growth Factor C
• Xenograft Model Antitumor Assays

Identifiers and source

Literature Corpus work

9fde025b-cc39-51f7-a13d-89c22f34cf9c

DOI

10.21203/rs.3.rs-8012028/v1