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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques

2024-07-30

Abstract excerpt

The continued evolution of SARS-CoV-2 variants capable of subverting vaccine and infection-induced immunity suggests the advantage of a broadly protective vaccine against betacoronaviruses (beta-CoVs). Recent studies have isolated monoclonal antibodies (mAbs) from SARS-CoV-2 recovered-vaccinated donors capable of neutralizing many variants of SARS-CoV-2 and other beta-CoVs. Many of these mAbs target the conserved...

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Literature Corpus work
9f6e8065-caf1-5929-95e1-1437ca23c7b3
DOI
10.1101/2024.07.30.605768
Open publication

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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaquesDOI 10.1101/2024.07.30.605768
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