Article

Small Extracellular Vesicles Derived From Human Ipsc-Derived MSC Ameliorate Tendinopathy-Related Acute Pain Through Inhibiting Mast Cells Activation

2021-12-06

Abstract excerpt

<h4>Background: </h4> Acute pain is the primary symptom of tendinopathy, and mast cells activation is a nonnegligible cause. Currently, safe and effective treatment for acute pain in tendinopathy is still lacking. This study was aimed to explore the analgesic effect of iPSC-derived mesenchymal stem cell-derived small extracellular vesicles (iMSC-sEVs) on acute pain and further investigate the underlying mechanisms...

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Literature Corpus work: 9f3e678a-cd2f-50ce-9fba-d8e829bea289
DOI: 10.21203/rs.3.rs-1130900/v1

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