Article

A negative feedback loop between Insulin-like Growth Factor signaling and the lncRNA SNHG7 tightly regulates transcript levels and proliferation

2019-07-22

Abstract excerpt

<h4>ABSTRACT</h4> Evidence suggests Insulin-like growth factor 1 (IGF1) signaling is involved in the initiation and progression of a subset of breast cancers by inducing cell proliferation and survival(1, 2). Although the signaling cascade following IGF1 receptor activation is well-studied(3, 4), the key elements of the transcriptional response governing IGF1’s actions are not well understood. Recent studies reve...

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Literature Corpus work: 9f2316f5-fe85-5d9c-b9be-f9a31f4369e0
DOI: 10.1101/709352

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