Development of Anti-HIV Therapeutics: From Conventional Drug Discovery to Cutting-Edge Technology

Abstract excerpt

With the first case of human immunodeficiency virus (HIV) infection confirmed in US in 1981, the efforts of discovering anti-HIV therapeutics have been continued ever since. Ten years later, the first HIV drug zidovudine (AZT) was developed to inhibit HIV reverse transcriptase. At meantime, scientists were enlightened to discover new drugs of different targets acting on HIV integrase, protease, and host receptors....

Topics

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• Acquired Immunodeficiency Syndrome
• Gene Editing
• Genetic Therapy
• HIV-1
• HIV/AIDS drug development and treatment
• HIV/AIDS Research and Interventions
• HIV Research and Treatment
• Immune Evasion

Identifiers and source

Literature Corpus work

9eb23850-6926-5e4f-802a-25e6f0176a30

DOI

10.20944/preprints202401.1662.v1