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Evaluating metagenomic sequencing as a stool-based diagnostic in children with presumptive TB in Uganda

2026-02-03

Abstract excerpt

<h4>Background</h4> Stool-based molecular tests are a noninvasive option for pediatric tuberculosis (TB) diagnosis, but have lower sensitivity compared to sputum-based tests. Untargeted metagenomic sequencing (mNGS) on stool could improve sensitivity and identify new gene targets for molecular testing. <h4>Methods</h4> We performed shotgun mNGS on DNA isolated from stool samples of children undergoing assessment...

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Literature Corpus work
9db090d9-8111-5106-8b59-28cfe93d754b
DOI
10.64898/2026.01.29.26345155
Open publication

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Evaluating metagenomic sequencing as a stool-based diagnostic in children with presumptive TB in UgandaDOI 10.64898/2026.01.29.26345155
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