Article

Efficacy of thalidomide treatment in children with transfusion dependent β-thalassemia: a retrospective clinical study

2021-02-24

Abstract excerpt

<h4>Background: </h4> Thalidomide has been reported as a promising treatment for reducing transfusion volume in adults with β-thalassemia. However, the evidence about the safety and efficacy of thalidomide on children with transfusion dependent β-thalassemia (TDT) is scarce. Methods Seventy-seven children with TDT treated with thalidomide at least for 6 months were included and retrospectively analyzed. Oral dose...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9da640fb-df2d-5f9c-b117-f88bb4d34372
DOI: 10.22541/au.161418357.76442615/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Efficacy of thalidomide treatment in children with transfusion dependent β-thalassemia: a retrospective clinical studyDOI 10.22541/au.161418357.76442615/v1Read

Clinical efficacy of thalidomide for various genotypes of beta thalassemiaSemantic proximity Read

Clinical efficacy of thalidomide for various genotypes of beta thalassemia.Semantic proximity Read

Report on patients with non transfusion-dependent β-thalassemia major being treated with hydroxyurea attending the Thalassemia Research Center, Sari, Mazandaran Province, Islamic Republic of Iran in 2013.Semantic proximity Read

[Predictors of Hematologic Responses in Patients with Non-Transfusion-Dependent β-Thalassemia Receiving Thalidomide Therapy].Semantic proximity Read

Genotype-phenotype relationship of patients with β-thalassemia taking hydroxyurea: a 13-year experience in Iran.Semantic proximity Read

Association of CYP2C19 gene single nucleotide polymorphisms (rs12248560 and rs4244285) with response to thalidomide in transfusion dependent β-thalassemia patients- a 12-months follow-up study.Semantic proximity Read

Drug repurposing: Hydroxyurea therapy improves the transfusion-free interval in HbE/beta-thalassemia–major patients with Xmn1 polymorphismSemantic proximity Read

The association of HBG2, BCL11A, and HBS1L-MYB polymorphisms to thalidomide response in Chinese β-thalassemia patients.Semantic proximity Read

Clinico-Hematological Profile and Management of Children With Non-Transfusion Dependent Thalassemia (NTDT) at a Pediatric Center in Northern India.Semantic proximity Read

Severity scoring system to guide transfusion management in pediatric non-deletional HbH.Semantic proximity Read

The Prevalence of HBB Mutations among the Transfusion-Dependent and Non Transfusion-Dependent Hb E/β-Thalassemia Children in a Tertiary Center of West Bengal, India.Semantic proximity Read

Low and fixed dose of hydroxyurea is effective and safe in patients with HbSβ(+) thalassemia with IVS1-5(G→C) mutation.Semantic proximity Read