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Disruption of nasal bacteria enhances protective immune responses to influenza A virus and SARS-CoV-2 infection in mice

2020-12-27

Abstract excerpt

Gut microbiota plays a critical role in the induction of adaptive immune responses to influenza virus infection. However, the role of nasal bacteria in the induction of the virus-specific adaptive immunity is less clear. Here we demonstrate that while intranasal administration of influenza virus hemagglutinin vaccine alone was insufficient to induce the vaccine-specific antibody responses, disruption of nasal bact...

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Identifiers and source

Literature Corpus work
9d628280-1efc-598a-b931-74fd6b5b1235
DOI
10.1101/2020.12.25.424300
Open publication

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Disruption of nasal bacteria enhances protective immune responses to influenza A virus and SARS-CoV-2 infection in miceDOI 10.1101/2020.12.25.424300
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