Article

Optical recordings of unitary synaptic connections reveal high and random local connectivity between CA3 pyramidal cells

2025-01-17

Abstract excerpt

The hippocampal CA3 region is thought to play crucial roles in episodic memory functions because of the extensive recurrent connections between CA3 pyramidal cells (CA3PCs). However, different methods provided contradicting observations about the synaptic connectivity between CA3PCs. Therefore, we estimated the connectivity rate between individual CA3PCs using a new approach that is not affected by the confounds o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9b9f7681-b803-5077-832d-a4b81a14f83a
DOI: 10.1101/2025.01.15.633173

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Optical recordings of unitary synaptic connections reveal high and random local connectivity between CA3 pyramidal cellsDOI 10.1101/2025.01.15.633173Read

Human hippocampal CA3 uses specific functional connectivity rules for efficient associative memorySemantic proximity Read

Cellular and Synaptic Diversity of Layer 2-3 Pyramidal Neurons in Human IndividualsSemantic proximity Read

Conditioning by Subthreshold Synaptic Input Changes the Intrinsic Firing Pattern of CA3 Hippocampal NeuronsSemantic proximity Read

Mapping Large-scale Spatiotemporal Dynamics of Synaptic Plasticity and LTP for Memory Encoding in the Hippocampal NetworkSemantic proximity Read

Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortexSemantic proximity Read

Presynaptic Endoplasmic Reticulum Contributes Crucially to Short-term Plasticity in Small Hippocampal SynapsesSemantic proximity Read

Book review of Electrophysiological Recording Techniques, edited by Robert P Vertes and Robert W Stackman, JrSemantic proximity Read

High-throughput microcircuit analysis of individual human brains through next-generation multineuron patch-clampSemantic proximity Read

A physical neural mass model framework for the analysis of oscillatory generators from laminar electrophysiological recordingsSemantic proximity Read

Quantitative firing pattern phenotyping of hippocampal neuron typesSemantic proximity Read

A databank for intracellular electrophysiological mapping of the adult somatosensory cortexSemantic proximity Read

A comprehensive knowledge base of synaptic electrophysiology in the rodent hippocampal formationSemantic proximity Read