Article

Papillary and Reticular Fibroblasts Generate Distinct Microenvironments that Differentially Impact Angiogenesis

2020-11-29

Abstract excerpt

<h4>ABSTRACT</h4> Papillary and reticular dermis show distinct extracellular matrix (ECM) and vascularization, and fibroblasts isolated from these compartments have different gene expression patterns and behaviour in vitro. However, due to lack of relevant models, the contribution of skin fibroblast sub-populations to vascularization remains unknown. We thus cultured human papillary and reticular fibroblasts as...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9b71f70c-671a-526c-9901-2dbd28b88542
DOI: 10.1101/2020.11.29.402594

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Papillary and Reticular Fibroblasts Generate Distinct Microenvironments that Differentially Impact AngiogenesisDOI 10.1101/2020.11.29.402594Read

Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinicSemantic proximity Read

Lineage Identity and Location within the Dermis Determine the Function of Papillary and Reticular Fibroblasts in Human SkinSemantic proximity Read

Fibroblasts from the Human Skin Dermo-Hypodermal Junction are Distinct from Dermal Papillary and Reticular Fibroblasts and from Mesenchymal Stem Cells and Exhibit a Specific Molecular Profile Related to Extracellular Matrix Organization and Modeling.Semantic proximity Read

Papillary fibroblasts differentiate into reticular fibroblasts after prolonged in vitro culture.Semantic proximity Read

Human Dermal Fibroblast Subpopulations Are Conserved across Single-Cell RNA Sequencing StudiesSemantic proximity Read

Deciphering the functional heterogeneity of skin fibroblasts using single‐cell RNA sequencingSemantic proximity Read

Fibroblast heterogeneity: more than skin deepSemantic proximity Read

Aging Alters Functionally Human Dermal Papillary Fibroblasts but Not Reticular Fibroblasts: A New View of Skin Morphogenesis and AgingSemantic proximity Read

New Anti‐Fibrotic Strategies for Keloids: Insights From Single‐Cell Multi‐OmicsSemantic proximity Read

Evidence of inter‐ and intra‐keloid heterogeneity through analysis of dermal fibroblasts: A new insight in deciphering keloid physiopathologySemantic proximity Read

Transcriptomic analysis of 3D vasculature-on-a-chip reveals paracrine factors affecting vasculature growth and maturationSemantic proximity Read

Transcriptomic Analysis of 3D Vasculature-On-A-Chip Reveals Paracrine Factors Affecting Vasculature Growth and MaturationSemantic proximity Read