Article

A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease

2021-10-15

Abstract excerpt

Advances in single cell multi-omics analysis such as the ability of a genotype to show phenotypic diversity lead to a comprehensive understanding of cellular events in human diseases. The cardinal feature to access this information is the technology used for single-cell isolation, barcoding, and sequencing. While numerous platforms have been reported for single-cell RNA-sequencing, technical enhancements are neede...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9b42b551-4f03-5252-80b7-af2acc86d14d
DOI: 10.21203/rs.3.rs-957427/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-diseaseDOI 10.21203/rs.3.rs-957427/v1Read

A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-diseaseSemantic proximity Read

A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease.Semantic proximity Read

The role of single-cell genomics in human genetics.Semantic proximity Read

Premature aging disorders: A clinical and genetic compendium.Semantic proximity Read

Deciphering the consequence of deep intronic variants: a progeroid syndrome caused by a<i>TAPT1</i>mutation is revealed by combined RNA/SI-NET sequencingSemantic proximity Read

Challenges and Opportunities for the Translation of Single-Cell RNA Sequencing Technologies to DermatologySemantic proximity Read

Single-cell genomics meets human genetics.Semantic proximity Read

High-throughput sequencing for biology and medicine.Semantic proximity Read

Charting the cellular landscape of pulmonary arterial hypertension through single-cell omicsSemantic proximity Read

Outcomes of 4 years of molecular genetic diagnosis on a panel of genes involved in premature aging syndromes, including laminopathies and related disorders.Semantic proximity Read

A progeroid syndrome caused by a deep intronic variant in TAPT1 is revealed by RNA/SI-NET sequencing.Semantic proximity Read

Research Techniques Made Simple: Whole-Transcriptome Sequencing by RNA-Seq for Diagnosis of Monogenic Disorders.Semantic proximity Read