Article

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

2022-04-15

Abstract excerpt

The mRNA SARS-CoV-2 vaccines were brought to market in response to the public health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious disease has no precedent. The many alterations in the vaccine mRNA hide the mRNA from cellular defenses and promote a longer biological half-life and high production of spike protein. However, the immune response to the vaccine is very different from...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9aff21ac-9510-558f-8973-c370eeeaca32
DOI: 10.1016/j.fct.2022.113008

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAsDOI 10.1016/j.fct.2022.113008Read

Innate Immune Suppression by SARS-CoV-2 mRNA Vaccinations: The role of G-quadruplexes, exosomes and microRNAsSemantic proximity Read

The Unique Features and Collateral Immune Effects of mRNA-Based COVID-19 Vaccines: Potential Plausible Causes of Adverse Events and ComplicationsSemantic proximity Read

mRNA Vaccines: Design Principles, Mechanisms, and Manufacturing—Insights From COVID‐19 as a Model for Combating Infectious DiseasesSemantic proximity Read

Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer–BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA VaccinesSemantic proximity Read

Engineering of the current nucleoside-modified mRNA-LNP vaccines against SARS-CoV-2Semantic proximity Read

Concern about the Effectiveness of mRNA Vaccination Technology and Its Long-Term Safety: Potential Interference on miRNA MachinerySemantic proximity Read

Exosome-Mediated mRNA Delivery For SARS-CoV-2 VaccinationSemantic proximity Read

Self-Amplifying RNA: A Second Revolution of mRNA Vaccines against COVID-19Semantic proximity Read

Single-cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccineSemantic proximity Read

Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccineSemantic proximity Read

In Gratitude for mRNA VaccinesSemantic proximity Read

Adverse effects of COVID-19 mRNA vaccines: the spike hypothesisSemantic proximity Read