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Simplifying the dental/periodontal management of patients with metabolic bone fragility receiving treatment with denosumab

2020-06-16

Abstract excerpt

Denosumab (DNB) is a bone-targeted medication used to preserve structural integrity and minimise the risk of fragility fractures in metastatic cancer and metabolic bone disorders. DNB targets and binds RANK Ligand, inhibiting osteoclast maturation, function, and survival. In contrast with nitrogen-containing bisphosphonates (N-BPs), DNB does not bind to hydroxyapatite and incorporate into bone; thus, bone cellular...

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Literature Corpus work
99d69876-f556-5990-9641-84e89213ca0a
DOI
10.32388/d95owg
Open publication

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