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Article

Denosumab: mechanism of action and clinical outcomes

12 Sept 2012

Abstract excerpt

AIMS: To describe the mechanisms of action of denosumab, a novel antiresorptive agent, contrasting it with other antiresorptive and anabolic osteoporosis treatments. METHODS: Published papers related to the mechanism of action of approved osteoporosis treatments were sought through MEDLINE searches. FINDINGS: Osteoporotic fractures carry a substantial burden of morbidity and mortality, but pharmacotherapy can...

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Identifiers

PMID: 22967310
DOI: 10.1111/ijcp.12022

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