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Single-cell transcriptomics identifies a p21-activated kinase important for survival of the zoonotic parasite <i>Fasciola hepatica</i>

2024-03-27

Abstract excerpt

Knowledge on the cell types and cell-specific gene expression of multicellular pathogens facilitates drug discovery and allows gaining a deeper understanding of pathogen biology. By utilizing single-cell RNA sequencing (scRNA-seq), we analyzed 19,581 cells of a globally prevalent parasitic flatworm, the liver fluke Fasciola hepatica, which causes a neglected tropical disease and zoonosis known as fascioliasis. We...

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Literature Corpus work
98de2eb2-c2e1-529d-90ec-813ad836f895
DOI
10.1101/2024.03.26.586785
Open publication

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Single-cell transcriptomics identifies a p21-activated kinase important for survival of the zoonotic parasite <i>Fasciola hepatica</i>DOI 10.1101/2024.03.26.586785
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