Article

Novel post-translational modification in voltage-gated potassium channel KCNQ2

2025-11-18

Abstract excerpt

<title>Abstract</title> <p> KCNQ2 is a member of the voltage-gated potassium (Kv) channel family and regulates neuronal activity through potassium ion efflux. Pathogenic variants of KCNQ2 lead to aberrant neuronal activity and cause two types of epilepsy: self-limited familial neonatal epilepsy (SLFNE) and developmental and epileptic encephalopathies (DEE). However, how these pathogenic variants influence KCNQ2...

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Literature Corpus work: 97f1532f-5e34-5238-bbf2-048056081bee
DOI: 10.21203/rs.3.rs-7965157/v1

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