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Article

Proteomic characterization of Sophoraflavone J-induced apoptosis in HepG2 cells.

2007-12-01

Abstract excerpt

Chinese herb Radix sophorae is widely applied as an anticarcinogenic/antimetastatic agent against liver cancers. In the current study, Sophoraflavone J, a flavonoid constituent enriched in the root of Radix sophorae, induced apoptosis in human hepatoma HepG2 cells via the intrinsic mitochondrial death pathway. The molecular mechanism of the cytotoxic effect was further investigated by a comparative proteomic appro...

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Identifiers and source

Literature Corpus work
97ce4620-af68-5d71-941e-8227af375b05
DOI
10.1002/prca.200601000
Open publication

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Proteomic characterization of Sophoraflavone J-induced apoptosis in HepG2 cells.DOI 10.1002/prca.200601000
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