Article

PIM2 kinase regulates the expression of TIGIT and energy metabolism on NK cell in multiple myeloma patients

2022-10-24

Abstract excerpt

<h4>Background: </h4> PIM2 kinase play a vital role in the generation of plasma cell and bone loss in multiple myeloma(MM), which highly related to the tumor progression and as a potential therapy target in MM. In immune cell,PIM2 kinase involved in the regulation of lymphocyte like T cell and B cell, However, its role in NK cells remains unclear. <h4>Methods: </h4>: Single-cell RNA sequencing data were analysed...

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Literature Corpus work: 97b3d90d-dbbe-5469-a2da-0cdfefdc8dfe
DOI: 10.21203/rs.3.rs-2159151/v1

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