Article
Single-Cell RNA Sequencing Reveals Hemocyte Heterogeneity, Differentiation Trajectories, and Viral Tropism in Shrimp ( <i>Macrobrachium rosenbergii</i> ) Infected with Decapod Iridescent Virus 1
2025-02-14
Abstract excerpt
Decapod Iridescent Virus 1 (DIV1) is a highly pathogenic virus threatening crustacean aquaculture. Hemocytes, the primary immune cells in shrimp, play crucial roles in host defense, yet their transcriptional heterogeneity and differentiation dynamics under viral infection remain poorly understood. Here, we characterize hemocyte subpopulations in Macrobrachium rosenbergii before and after DIV1 infection at single-...
Topics
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- Aquaculture disease management and microbiota
- Cytomegalovirus and herpesvirus research
- Gene Expression Profiling
- High-Throughput Nucleotide Sequencing
- Insect symbiosis and bacterial influences
- Invertebrate Immune Response Mechanisms
- Mosquito-borne diseases and control
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 97138021-904f-566b-a77e-bbc91222b5d2
- DOI
- 10.1101/2025.02.10.637476
