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Single-cell analysis of mosquito hemocytes identifies signatures of immune cell subtypes and cell differentiation

28 Jul 2021

Abstract excerpt

Mosquito immune cells, known as hemocytes, are integral to cellular and humoral responses that limit pathogen survival and mediate immune priming. However, without reliable cell markers and genetic tools, studies of mosquito immune cells have been limited to morphological observations, leaving several aspects of their biology uncharacterized. Here, we use single-cell RNA sequencing (scRNA-seq) to characterize...

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PMID: 34318744
DOI: 10.7554/elife.66192

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