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P53 loss and BRAF V600E mutation represent divergent pathways to aggressiveness in high grade differentiated thyroid carcinoma

2026-04-24

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : High-grade differentiated thyroid carcinoma (HGDTC) is a newly defined tumor entity in the 2022 WHO classification of thyroid tumors. Its diagnostic criteria, molecular characteristics, and clinical management system are still not fully developed, posing significant challenges for clinical diagnosis and treatment. <bold>Case Report</bold> : Case 1 was a 75...

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Literature Corpus work
96c1a343-9102-5c6e-a52b-e9ad263c699e
DOI
10.21203/rs.3.rs-9194773/v1
Open publication

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P53 loss and BRAF V600E mutation represent divergent pathways to aggressiveness in high grade differentiated thyroid carcinomaDOI 10.21203/rs.3.rs-9194773/v1
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