Article

Humoral immunity to endemic coronaviruses in older adults increases post-COVID-19 vaccination and in correlation with their anti-SARS-CoV-2 responses

2025-08-27

Abstract excerpt

Advanced age is an established risk factor for SARS-CoV-2 infection and severe disease. Older adults, having experienced recurrent infections with human endemic coronaviruses (HCoVs) throughout life, may have developed humoral immune responses that impact IgG targeting of both severe acute respiratory syndrome coronavirus (SARS-CoV) −2 and HCoVs. We profiled IgG responses in community-dwelling adults aged 50-87 ye...

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Literature Corpus work: 96a58105-d180-5e48-bf3d-df9ffb81d940
DOI: 10.1101/2025.08.26.25334476

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