Article
Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights<i>APOL1</i>as a high risk locus in patients with diabetic macular edema
2023-01-25
Abstract excerpt
Diabetic retinopathy (DR) is a common complication of diabetes. Approximately 20% of DR patients have diabetic macular edema (DME) characterized by fluid leakage into the retina. There is a genetic component to DR and DME risk, but few replicable loci. Because not all DR cases have DME, we focused on DME to increase power, and conducted a multi-ancestry GWAS to assess DME risk in a total of 1,502 DME patients and...
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Identifiers and source
- Literature Corpus work
- 966c59b5-1638-5631-b05f-46b7fbabb5fc
- DOI
- 10.1101/2023.01.23.23284446