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Infectious Complications of Cyclin-Dependent Kinases 4 and 6 Inhibitors in Patients With Hormone Receptor-Positive Metastatic Breast Cancer: A Systematic Review and Meta-analysis

2022-03-02

Abstract excerpt

<title>Abstract</title> <p><bold>Aim:</bold> The combination of cyclin-dependent kinase 4 and 6 (CDK 4/6) inhibitors plus endocrine therapy (ET) improved the survival outcomes and became standard of care in the treatment of metastatic hormone-positive breast cancer. However, these combinations increased the risk of neutropenia compared with ET alone. While the infection-related mortalities did not seem to be incr...

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Literature Corpus work
960caa80-59fc-537c-a062-cacfc4881615
DOI
10.21203/rs.3.rs-1270186/v1
Open publication

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Infectious Complications of Cyclin-Dependent Kinases 4 and 6 Inhibitors in Patients With Hormone Receptor-Positive Metastatic Breast Cancer: A Systematic Review and Meta-analysisDOI 10.21203/rs.3.rs-1270186/v1
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