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The Crosstalk Between CTNNB1 Mutation and M2 Macrophages Contribute to Hepatocellular Carcinoma Suppressive Immune Microenvironment

2022-10-20

Abstract excerpt

<h4>Objective: </h4> Mutations in the CTNNB1 gene was the second most common mutation after TP53 in HCC. However, the CTNNB1 mutation and tumor immune microenvironment of HCC have not been clarified. <h4>Materials: </h4> and Methods: We compared the CTNNB1 mutation frequency and hotspot site in China Pan-cancer (OrigiMed2020) and TCGA PanCancer Atlas cohort via cBioPortal database. The differentially expressed ge...

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Literature Corpus work
95ac4cfd-2746-5226-aa5b-fd7f4825c0e2
DOI
10.21203/rs.3.rs-2176946/v1
Open publication

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