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Higher Blood-to-Tissue Tumor Mutational Burden Ratio Is Associated With Poorer Overall Survival in Advanced Non-Small Cell Lung Cancer

2026-08-06

Abstract excerpt

<h4>Introduction</h4> Blood-based and tissue-based tumor mutational burden (bTMB and tTMB) show only moderate concordance in advanced non-small cell lung cancer (NSCLC). We hypothesized that discordance between the two measures reflects tumor heterogeneity and carries prognostic information beyond either measure alone. <h4>Methods</h4> We retrospectively identified 105 patients with advanced NSCLC who underwent...

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Literature Corpus work
954e46f3-ccf2-550e-bed1-a5910969b1f8
DOI
10.64898/2026.08.04.26359280
Open publication

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Higher Blood-to-Tissue Tumor Mutational Burden Ratio Is Associated With Poorer Overall Survival in Advanced Non-Small Cell Lung CancerDOI 10.64898/2026.08.04.26359280
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