Article

Berberine impairs spermatogenesis in mice by modulating ornithine metabolism via gut microbiota regulation

2023-11-02

Abstract excerpt

Berberine (BBR) is used to treat diarrhea clinically, its reproductive toxicity, however, is poorly documented. This study aims to investigate the impact of BBR on the male reproductive system. Gradient doses of BBR were administered orally to experimental mice for consecutive 14 days. The gut microbiota, sperm concentration of cauda epididymis, and serum testosterone levels were measured after the last dose for a...

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Literature Corpus work: 950c01e3-dfca-53d9-90b6-c9b29e8c2f3b
DOI: 10.1101/2023.10.30.564855

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