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PBMC-derived TBX21/GATA3 and RORC2/FOXP3 expression ratios are associated with thyroid autoantibody positivity in adults with type 1 diabetes: an exploratory cross-sectional study

2026-08-28

Abstract excerpt

<title>Abstract</title> <p>Background Thyroid autoimmunity is common in type 1 diabetes mellitus (T1DM), but its relationship to lineage-associated transcription-factor expression in mixed peripheral blood mononuclear cells (PBMCs) remains uncertain. We examined whether PBMC-derived TBX21/GATA3 and RORC2/FOXP3 expression ratios were associated with thyroid autoantibody status and whether corresponding PBMC trans...

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Literature Corpus work
94816cff-a008-510f-9935-f0e7516f6090
DOI
10.21203/rs.3.rs-10447632/v1
Open publication

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PBMC-derived TBX21/GATA3 and RORC2/FOXP3 expression ratios are associated with thyroid autoantibody positivity in adults with type 1 diabetes: an exploratory cross-sectional studyDOI 10.21203/rs.3.rs-10447632/v1
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