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Dual human milk oligosaccharide-fibre utilisation drives gut microbiome selection during weaning

2025-07-24

Abstract excerpt

Gut microbiome (GM) maturation in early life follows organised taxonomic successions. How weaning impacts these trajectories remains underexplored. Here, we sampled faeces from seven mother-infant dyads at pre-, early and late weaning. Enrichment cultures (n=306) and metagenomic (n=108) analyses revealed an unexpected prevalence of fibre degradation genes and the growth of the pre-weaning infant GM on common dieta...

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Literature Corpus work
941da19d-c3ac-5d79-b003-5aae9f54acce
DOI
10.1101/2025.07.24.666491
Open publication

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Dual human milk oligosaccharide-fibre utilisation drives gut microbiome selection during weaningDOI 10.1101/2025.07.24.666491
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