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Immunogenicity, efficacy, and safety of SARS-CoV-2 vaccine dose fractionation: a systematic review and meta-analysis

2022-06-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Dose fractionation of Coronavirus Disease 2019 (COVID-19) vaccine could effectively accelerate global vaccine coverage, while supporting evidence of efficacy, immunogenicity, and safety are unavailable, especially with emerging variants.<bold>Methods:</bold> We systematically reviewed clinical trials reported dose-finding results and estimated the dose-response...

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Literature Corpus work
9350f886-210f-5bc4-99f1-10a94e4a6c00
DOI
10.21203/rs.3.rs-1571821/v2
Open publication

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