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Article

Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes.

Science (New York, N.Y.) - 23 Apr 2021

Saad-Roy Chadi M, Morris Sinead E, Metcalf C Jessica E, Mina Michael J, Baker Rachel E, Farrar Jeremy, Holmes Edward C, Pybus Oliver G, Graham Andrea L, Levin Simon A, Grenfell Bryan T, Wagner Caroline E

Abstract excerpt

Given vaccine dose shortages and logistical challenges, various deployment strategies are being proposed to increase population immunity levels to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Two critical issues arise: How timing of delivery of the second dose will affect infection dynamics and how it will affect prospects for the evolution of viral immune escape via a buildup of partially immune...

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Source

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Identifiers

PMID: 33688062
DOI: 10.1126/science.abg8663
PMCID: PMC8128287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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