Article
Allele-specific methylation of the PSA promoter in prostate cells: a new translational marker for the differential diagnosis of prostate cancer
2023-09-20
Abstract excerpt
<h4>Background: </h4> DNA methylation is one of the mechanisms of epigenetic control of gene expression and a change in the intrinsic pattern can lead to various diseases and disorders. At the same time, this makes DNA methylation a disease-specific biomarker. Here, we show that the acquisition of biallelic methylation status or even biallelic lack of methylation by the PSA promoter is a characteristic feature of...
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Identifiers and source
- Literature Corpus work
- 92de1498-ef95-5da1-865c-e304bc206de3
- DOI
- 10.21203/rs.3.rs-3352629/v1