Article

Variation in <i>Leishmania</i> chemokine suppression driven by diversification of the GP63 virulence factor

2021-02-02

Abstract excerpt

Leishmaniasis is a neglected tropical disease with diverse infection outcomes ranging from self-healing lesions, to progressive non-healing lesion, to metastatic spread and destruction of mucous membranes. Although resolution of cutaneous leishmaniasis is a classic example of type-1 immunity leading to well controlled self-healing lesions, an excess of type-1 related inflammation can contribute to immunopathology...

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Literature Corpus work: 92c6298e-f511-5f55-8718-6fed4c3674cd
DOI: 10.1101/2021.02.01.429140

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