Article

Interactions between species introduce spurious associations in microbiome studies

2017-08-15

Abstract excerpt

Microbiota contribute to many dimensions of host phenotype, including disease. To link specific microbes to specific phenotypes, microbiome-wide association studies compare microbial abundances between two groups of samples. Abundance differences, however, reflect not only direct associations with the phenotype, but also indirect effects due to microbial interactions. We found that microbial interactions could eas...

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Identifiers and source

Literature Corpus work: 92972e90-4152-5acc-b227-c8d09b187e32
DOI: 10.1101/176677

Open publication

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