Article

The skin commensal yeast <i>Malassezia</i> promotes tissue homeostasis via the aryl hydrocarbon receptor

2025-03-26

Abstract excerpt

<h4>ABSTRACT</h4> As an abundant fungal colonizer of human skin, Malassezia has long been associated with pathological skin conditions, yet its role in skin homeostasis remain poorly understood. Here, we demonstrate that Malassezia furfur plays an active role in maintaining epidermal integrity by producing tryptophan-derived metabolites that activate the aryl hydrocarbon receptor (AhR), a key regulator of kerat...

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Literature Corpus work: 9264af6d-a48a-5d3e-8cbc-078c18841866
DOI: 10.1101/2025.03.26.645515

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