Article

Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors Induced Neurocognitive Disorder: A Pharmacovigilance Study by Analyzing the Data from the U.S. FDA Adverse Event Reporting System

2021-12-08

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold>The neurocognitive disorder is a rare adverse event associated with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) inhibitors in the randomized controlled trail (RCTs), there was limited evidence to prove their relation. This study aimed to assessing their association by detecting adverse signal in the FDA Adverse Event Reporting System (FAERS).<bold>Methods</...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 911f4426-e0c7-5a58-a66c-c17bef9d0ffb
DOI: 10.21203/rs.3.rs-831924/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors Induced Neurocognitive Disorder: A Pharmacovigilance Study by Analyzing the Data from the U.S. FDA Adverse Event Reporting SystemDOI 10.21203/rs.3.rs-831924/v1Read

PCSK9 Inhibitors Do Not Increase Cognitive RiskSemantic proximity Read

Pharmacovigilance analysis of inclisiran:a real-world assessment based on the FAERS databaseSemantic proximity Read

Adverse event analysis and signal detection of calcitonin gene-related peptide inhibitors using the FDA Adverse Event Reporting System databaseSemantic proximity Read

Pharmacovigilance Insights into Gastrointestinal Adverse Events of JAK Inhibitors: FAERS Signal Detection with Clinical and Pharmacological ImplicationseSemantic proximity Read

Causal relationship between PCSK9 inhibitor and common neurodegenerative diseases: A drug target Mendelian randomization study.Semantic proximity Read

A real-world pharmacovigilance study of FDA Adverse Event Reporting System (FAERS) events for OsimertinibSemantic proximity Read

Signal Mining for Non-Bleeding Adverse Event in Novel Oral Anticoagulants: A Pharmacovigilance Study Based on the FAERS DatabaseSemantic proximity Read

A Real-World Pharmacovigilance Study of Ceftazidime/avibactam: Data Mining of the FDA Adverse Event Reporting System (FAERS) DatabaseSemantic proximity Read

The Adverse Event Atlas and Signal Consensus Index: A Multi-Source Pharmacovigilance PlatformSemantic proximity Read

Adverse reactions associated with the use of ustekinumab in Crohn's disease treatment：an analysis based on the FAERS databaseSemantic proximity Read

Real-world safety of zonisamide: Mining and analysis of adverse events related to zonisamide based on FAERS databaseSemantic proximity Read

Neuropsychiatric adverse reactions of leukotriene receptor antagonist, antihistamine and inhaled corticosteroid: A real-world analysis of the Food and Drug Administration (FDA) Adverse Event ReportingSemantic proximity Read