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Article

Human Skin as an Ex Vivo Model for Mycobacterium leprae Maintenance and Studies of Leprosy

2024-05-13

Abstract excerpt

The in vitro cultivation of M. leprae has not been possible since it was described as causing leprosy, and the limitation of animal models for clinical aspects makes studies on leprosy and bacteria-human host interaction a challenge. Our aim was to standardize the ex vivo skin model (hOSEC) to maintenance and study of M. leprae as an alternative animal model. Bacillary suspensions were inoculated into human skin e...

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Literature Corpus work
90e2a802-c209-56cf-9952-f224395d952c
DOI
10.20944/preprints202405.0887.v1
Open publication

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Human Skin as an Ex Vivo Model for Mycobacterium leprae Maintenance and Studies of LeprosyDOI 10.20944/preprints202405.0887.v1
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