Article

A Genotype-to-Phenotype Modeling Framework to Predict Human Pathogenicity of Novel Coronaviruses

2021-09-20

Abstract excerpt

Leveraging prior viral genome sequencing data to make predictions on whether an unknown, emergent virus harbors a ‘phenotype-of-concern’ has been a long-sought goal of genomic epidemiology. A predictive phenotype model built from nucleotide-level information alone has previously been considered un-tenable with respect to RNA viruses due to the ultra-high intra-sequence variance of their genomes, even within closel...

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Literature Corpus work: 908c299e-5c24-587e-ac0a-7b7749de1edc
DOI: 10.1101/2021.09.18.460926

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