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Article

Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

2020-04-08

Abstract excerpt

SARS-CoV-2 poses an immediate, major threat to public health across the globe. Here we report an in-depth molecular analysis to reconstruct the evolutionary origins of the enhanced pathogenicity of SARS-CoV-2 and other coronaviruses that are severe human pathogens. Using integrated comparative genomics and machine learning techniques, we identify key genomic features that differentiate SARS-CoV-2 and the viruses b...

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Literature Corpus work
0f5a2b49-18e6-5e41-b1ab-4f74ec2d6ae5
DOI
10.1101/2020.04.05.026450
Open publication

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Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronavirusesDOI 10.1101/2020.04.05.026450
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