Back to search

Article

Cuproptosis is correlated with clinical status, tumor immune microenvironment and immunotherapy in colorectal cancer: a multi-omic analysis

2022-09-14

Abstract excerpt

<h4>ABSTRACT</h4> Copper, like double-edged sword, either too little or too much can lead to cell death. Cuproptosis, a novel identified cell death form induced by copper, is characterized by aggregation of lipoylated mitochondrial enzymes and the destabilization of Fe–S cluster proteins. However, the function and potential clinical value of cuproptosis in colorectal cancer remains largely unknown. In this study,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9082ff69-efe5-5800-8a52-ab5bc0150b27
DOI
10.1101/2022.09.12.507555
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Cuproptosis is correlated with clinical status, tumor immune microenvironment and immunotherapy in colorectal cancer: a multi-omic analysisDOI 10.1101/2022.09.12.507555
A novel cuproptosis-related molecular pattern and its tumor microenvironment characterization in colorectal cancerSemantic proximity
Evaluating the Impact of Cuproptosis-Related Genes on Prognosis and the Tumor Microenvironment in Colon CancerSemantic proximity
Single-cell and Multi-omics Analysis Confirmed the Signature and Potential Targets of Cuproptosis in Colorectal CancerSemantic proximity
TIGD1 Function as a Potential Cuproptosis Regulator Following a Novel Cuproptosis-Related Gene Risk Signature in Colorectal CancerSemantic proximity
Identification and Validation of Cuproptosis-Related Genes in Prognosis and immune microenvironment in colon cancer patientsSemantic proximity
Molecular Function Validation and Prognostic Value Analysis of the Cuproptosis-Related Gene Ferredoxin 1 in Colon CancerSemantic proximity
The molecular mechanism and therapeutic landscape of copper and cuproptosis in cancerSemantic proximity
Integrative analysis of single-cell and bulk RNA seq to reveal the prognostic model and tumor microenvironment remodeling mechanisms of cuproptosis-related genes in colorectal cancerSemantic proximity
Cuproptosis-Related Risk Score Model Predicts Prognosis and Immune Characteristics of Esophageal CancerSemantic proximity
Pan-cancer patterns of cuproptosis markers reveal biologically and clinically relevant cancer subtypesSemantic proximity
Pan‐cancer analyses reveal molecular and clinical characteristics of cuproptosis regulatorsSemantic proximity
Comprehensive Analysis of Cuproptosis-related Genes Involved in Prognosis and Tumor Microenvironment Infiltration of Colorectal CancerSemantic proximity
Select a neighboring publication to make it the new centre.