Article
Propranolol reduces Parkinson’s tremor and inhibits tremor-related activity in the motor cortex: a placebo-controlled crossover trial
2024-08-02
Abstract excerpt
<h4>Objective</h4> Parkinson’s disease (PD) resting tremor is thought to be initiated in the basal ganglia and amplified in the cerebello-thalamo-cortical circuit. Since stress worsens tremor, the noradrenergic system may play a role in amplifying tremor. We tested if and how propranolol, a non-selective beta-adrenergic receptor antagonist, reduces PD tremor, and whether or not this effect is specific to stressful...
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Identifiers and source
- Literature Corpus work
- 90767dc2-dfe9-5864-8be9-64b4c11878d6
- DOI
- 10.1101/2024.08.01.24311354