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Article

CpG island status as an epigenetic alteration for NIS promoter in thyroid neoplasms; a cross- sectional study with a systematic review

2022-08-12

Abstract excerpt

<h4>Background: </h4> Gene silence via methylation of the CpG island is the most common epigenetic modification in cancer. Aberrant DNA methylation interferes with active transcription and is also significantly associated with poor tumor differentiation and prognosis. Given the highly significant role of NIS in thyroid cancer differentiation, this cross-sectional study aimed to investigate the DNA methylation patt...

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Literature Corpus work
9006bc6f-7b93-5b07-9f6b-1d5d9a6f4dee
DOI
10.21203/rs.3.rs-1944653/v1
Open publication

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CpG island status as an epigenetic alteration for NIS promoter in thyroid neoplasms; a cross- sectional study with a systematic reviewDOI 10.21203/rs.3.rs-1944653/v1
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