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Mutagenesis of the Ammonium Transporter <i>AcAmt</i> Reveals a Reproductive Role and a Novel Ammonia-Sensing Mechanism in the Malaria Vector Mosquito <i>Anopheles coluzzii</i>

2021-01-31

Abstract excerpt

Anopheline mosquitoes are the sole vectors of malaria and rely on olfactory cues for host seeking in which ammonia derived from human sweat plays an essential role. To investigate the function of the Anopheles coluzzii ammonium transporter ( AcAmt ) in the mosquito olfactory system, we generated an AcAmt null mutant line using CRISPR/Cas9. AcAmt -/- mutants displayed a series of novel phenotypes compared with...

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Literature Corpus work
8f4ab0d0-58f5-5434-8f46-8fe1d5e9fd26
DOI
10.1101/2021.01.29.428879
Open publication

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Mutagenesis of the Ammonium Transporter <i>AcAmt</i> Reveals a Reproductive Role and a Novel Ammonia-Sensing Mechanism in the Malaria Vector Mosquito <i>Anopheles coluzzii</i>DOI 10.1101/2021.01.29.428879
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