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Article

An expanded neurogenetic toolkit to decode olfaction in the African malaria mosquito Anopheles gambiae

1 Feb 2024

Abstract excerpt

Anopheles gambiae uses its sense of smell to hunt humans. We report a two-step method yielding cell-type-specific driver lines for enhanced neuroanatomical and functional studies of its olfactory system. We first integrated a driver-responder-marker (DRM) system cassette consisting of a linked T2A-QF2 driver, QUAS-GFP responder, and a gut-specific transgenesis marker into four chemoreceptor genes (Ir25a, Ir76b,...

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PMID: 38412833
DOI: 10.1016/j.crmeth.2024.100714

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