Article

A newly identified pathology of Episodic Angioedema with Hypereosinophilia (Gleich’s Syndrome) revealed by Multi-Omics Analysis

2024-10-01

Abstract excerpt

Episodic Angioedema with Eosinophilia (Gleich syndrome) is a rare disease characterized by periodic angioedema, fever, and marked eosinophilia. This study aimed to elucidate the pathogenic factors of severe Gleich syndrome through comprehensive multi-omics analysis, including whole genome sequencing (WGS) and RNA sequencing (RNA-seq). A young female patient (age: 16-20 years old) presenting with periodic high feve...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8f28d661-fbd4-5aa8-a805-a1c3727b430d
DOI: 10.1101/2024.09.29.24313285

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A newly identified pathology of Episodic Angioedema with Hypereosinophilia (Gleich’s Syndrome) revealed by Multi-Omics AnalysisDOI 10.1101/2024.09.29.24313285Read

Unveiling the Complexities of Hereditary Angioedema.Semantic proximity Read

Disease-modifying factors in hereditary angioedema: an RNA expression-based screening.Semantic proximity Read

Bradykinin-Mediated Angioedema: An Update of the Genetic Causes and the Impact of GenomicsSemantic proximity Read

Identification of noninvasive and disease-specific biomarkers in hereditary angioedema using urinary proteomicsSemantic proximity Read

In Silico Analysis and In-depth Assessment of a Female Patient with a Missense Mutation in the F12 Gene Associated with Hereditary Angioedema Symptoms: A Case StudySemantic proximity Read

Novel Variants and Mechanisms in Atypical Hereditary Angioedema: A Chinese Multicenter StudySemantic proximity Read

Lethal COVID-19 Associates With RAAS-Induced Inflammation For Multiple Organ Damage Including Mediastinal Lymph NodesSemantic proximity Read

Hemophilia and hereditary angioedema: parallel therapeutic advances in genetic diseases of serine protease pathways.Semantic proximity Read

In depth transcriptomic profiling defines a landscape of dysfunctional immune responses in patients with VEXAS syndromeSemantic proximity Read

Endotypes, phenotypes, and biomarkers in chronic spontaneous urticaria: Evolving toward personalized medicine.Semantic proximity Read

Hidradenitis Suppurativa: A Perspective on Genetic Factors Involved in the DiseaseSemantic proximity Read

Integrative analysis reveals the role of THBS1 in IgG4-related diseaseSemantic proximity Read