Article
Accelerating manufacturing to enable large-scale supply of a new adenovirus-vectored vaccine within 100 days
2021-12-23
Abstract excerpt
The Coalition for Epidemic Preparedness Innovations’ ‘100-day moonshot’ aspires to launch a new vaccine within 100 days of pathogen identification. Here, we describe work to optimize adenovirus vector manufacturing for rapid response, by minimizing time to clinical trial and first large-scale supply, and maximizing the output from the available manufacturing footprint. We describe a rapid viral seed expansion work...
Topics
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- CAR-T cell therapy research
- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Outbreaks Research
- Viral Infectious Diseases and Gene Expression in Insects
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- 8dabe14a-2d19-523a-abef-d13da8958337
- DOI
- 10.1101/2021.12.22.473478
